Priligy contains dapoxetine hydrochloride equivalent to 30 mg or 60 mg dapoxetine. Priligy is indicated for the treatment of premature ejaculation (PE) in adult men aged 18 to 64 years. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin’s action at the post synaptic cleft, and as a consequence promoting ejaculatory delay.
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Dapoxetine was initially created as an antidepressant. Dapoxetine is absorbed and eliminated rapidly in the body. Its fast acting property makes it suitable for the treatment of PE but not as an antidepressant. Priligy should only be prescribed to patients who has problem with intravaginal ejaculatory latency time (IELT) of less than two minutes, persistent or recurrent ejaculation with minimal sexual stimulation before, on, or shortly after penetration and before the patient wishes, marked personal distress or interpersonal difficulty as a consequence of PE, poor control over ejaculation, history of premature ejaculation in the majority of intercourse attempts over the prior 6 months. Priligy should not be prescribed to delay ejaculation in men who have not been diagnosed with PE. Priligy is not intended for continuous daily use. Priligy should be taken only when sexual activity is anticipated. Priligy must not be taken more frequently than once every 24 hours. The medicine is for oral use. Tablets should be swallowed whole to avoid the bitter taste. It is recommended that tablets be taken with at least one full glass of water. Priligy may be taken with or without food. Avoid alcohol when taking this medicine. Drinking alcohol while taking this medicine may increase your risk of injury from fainting or from other side effects. The recommended dose is 30 mg. Take the medicine 1 to 3 hours before sexual activity is anticipated. Priligy should not be used in men with erectile dysfunction (ED) who are using PDE5 inhibitors. Priligy is not indicated for use by women. Priligy should not be used in men with moderate to severe hepatic impairment and in those receiving CYP3A4 inhibitors such as ketoconazole, ritonavir, and telithromycin, patients with heart failure, permanent pacemaker, or other significant ischemic heart disease. Do not take Priligy at the same time when you take medicines for depression called monoamine oxidase inhibitors, Thioridazine used for schizophrenia, medicine for depression, Lithium − a medicine for bipolar disorder, Nefazodone − an antidepressant, Linezolid − an antibiotic used to treat infections, Tryptophan − a medicine to help you sleep, St John’s wort − a herbal medicine, Tramadol − used to treat serious pain, medicines used to treat migraines.
If you have taken any of these medicines, you will need to wait 14 days after you stop taking it before you can start taking Priligy. Once you have stopped taking Priligy, you will need to wait 7 days before taking any of the medicines. Do not take the medicine when you are having epilepsy, blood clotting problems, kidney problems, and history of dizziness from low blood pressure, use recreational drugs like as ecstasy, LSD, narcotics or benzodiazepines, have mental health problem such as depression, mania or bipolar disorder. The medicine comes in Priligy 30 mg film−coated tablets and Priligy 60 mg film−coated tablets.